Is obesity associated with gastropharyngeal reflux disease?

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Jan 14, 2008 (publication date) through Feb 6, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2008; 14(2): 265-271
Published online Jan 14, 2008. doi: 10.3748/wjg.14.265

Table 1 Patient profiles and the endoscopic findings according to the body mass index

	Body mass index (kg/m²)			P value
	< 23 (n = 344)	23-25 (n = 231)	>25 (n = 194)
Age (yr, mean ± SEM)	48.4 ± 0.7	51.5 ± 0.7	53.8 ± 0.8	< 0.001
Gender (%)				0.077
Men	123 (35.8)	104 (45.0)	80 (41.2)
Women	221 (64.2)	127 (55.0)	114 (58.8)
Alcohol intake Smoking	66 (19.2)	50 (21.6)	55 (28.4)	0.048
Alcohol intake Smoking	42 (12.2)	31 (13.4)	33 (17.0)	0.295
Indication for pH monitoring (%)				0.210
Globus	156 (45.3)	100 (43.3)	86 (44.3)
Hoarseness	76 (22.1)	60 (26.0)	54 (27.8)
Coughing	54 (15.7)	46 (19.9)	26 (16.4)
Others¹	58 (16.9)	25 (10.8)	28 (14.4)
Endoscopic findings (%)
Reflux esophagitis²	32/291 (11.0)	19/204 (9.3)	32/166 (19.3)	0.009
Hiatal Hernia	15/291 (5.2)	19/204 (9.3)	12/166 (7.2)	0.199
Endoscopically suspected esophageal metaplasia	18/291 (6.2)	18/204 (8.8)	16/166 (9.6)	0.348

¹Other indications were halitosis, throat clearing and laryngeal pathology such as vocal polyp;

²Los Angeles classification grade.

Citation: Choi CW, Kim GH, Song CS, Wang SG, Lee BJ, I H, Kang DH, Song GA. Is obesity associated with gastropharyngeal reflux disease? World J Gastroenterol 2008; 14(2): 265-271
URL: https://www.wjgnet.com/1007-9327/full/v14/i2/265.htm
DOI: https://dx.doi.org/10.3748/wjg.14.265