Hepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cells

doi:10.3748/wjg.14.2877

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May 14, 2008 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 14, 2008; 14(18): 2877-2881
Published online May 14, 2008. doi: 10.3748/wjg.14.2877

Table 4 Core proteins of different quasispecies of HCV genotype 1b inhibited Chang liver cell cycle by impairing G1 to S transition at 72 h after transfection

	G0/G1 phase	S phase	G2/M phase
T	68.45 ± 4.98^a	14.79 ± 3.76^a	16.75 ± 3.21
NT	67.21 ± 5.47^a	16.17 ± 2.55^a	16.63 ± 2.95
C191	66.77 ± 4.32^a	16.38 ± 2.11^a	16.86 ± 2.19
pEGFP-N1	56.97 ± 3.29	27.48 ± 3.37	15.54 ± 1.93

^aP < 0.05 vs pEGFP-N1.

Citation: Yan XB, Mei L, Feng X, Wan MR, Chen Z, Pavio N, Brechot C. Hepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cells. World J Gastroenterol 2008; 14(18): 2877-2881
URL: https://www.wjgnet.com/1007-9327/full/v14/i18/2877.htm
DOI: https://dx.doi.org/10.3748/wjg.14.2877