Hepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cells

doi:10.3748/wjg.14.2877

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May 14, 2008 (publication date) through Aug 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 14, 2008; 14(18): 2877-2881
Published online May 14, 2008. doi: 10.3748/wjg.14.2877

Table 3 Core proteins of different quasispecies of HCV genotype 1b inhibited Chang liver cell cycle by impairing G1 to S transition at 48 h after transfection

	G0/G1 phase	S phase	G2/M phase
T	68.23 ± 6.54^a	15.30 ± 3.12^a	16.46 ± 2.57
NT	66.14 ± 5.33^a	16.38 ± 2.21^a	17.47 ± 3.74
C191	66.41 ± 3.02^a	15.92 ± 2.93^a	16.99 ± 2.43
pEGFP-N1	58.72 ± 2.23	25.69 ± 2.41	15.62 ± 1.28

^aP < 0.05 vs pEGFP-N1.

Citation: Yan XB, Mei L, Feng X, Wan MR, Chen Z, Pavio N, Brechot C. Hepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cells. World J Gastroenterol 2008; 14(18): 2877-2881
URL: https://www.wjgnet.com/1007-9327/full/v14/i18/2877.htm
DOI: https://dx.doi.org/10.3748/wjg.14.2877