Mitochondrial protection by low doses of insulin-like growth factor-Iin experimental cirrhosis

Table 2 Activities of the electron transport complexes (n = 6)

	CO, healthy control group	CI, untreated cirrhotic group	CI + IGF, cirrhotic rats treated with IGF-I
I-NADH-ubiquinone oxidoreductase (nmol/min per mg prot)	7.68 ± 2.19	11.01 ± 1.60c	16.10 ± 2.03
II-Succinate-ubiquinone oxidoreductase (&mgr;mol/min per mg prot)	0.38 ± 0.02	0.33 ± 0.04	0.35 ± 0.03
III-Ubiquinol-ferricytochrome oxidoreductase (nmol/min per mg prot)	89.57 ± 6.54	148.75 ± 23.26a	163.15 ± 21.38b
IV-Ferrocytochrome c-oxygen oxidoreductase (pmol/min per mg prot)	3.91 ± 0.85	5.22 ± 1.01	5.66 ± 0.97

mean ± SEM;

^aP < 0.05,

^bP < 0.01 vs CO groups;

^cP < 0.05 vs CI + IGF.