Anti-inflammatory activity of probiotic Bifidobacterium: Enhancement of IL-10 production in peripheral blood mononuclear cells from ulcerative colitis patients and inhibition of IL-8 secretion in HT-29 cells

Figure 1 Effects of probiotic bifidobacteria on IL-10 production in PBMNC. PBMNC were isolated from 9 ulcerative-colitis patients and incubated with heat-killed probiotic BbiY or BbrY (10 &mgr;g/mL), or LPS. At forty-eight hours after incubation, the IL-10 concentration was determined by ELISA (mean ± SD, n = 3). ^aP < 0.05, ^bP < 0.01 vs BbiY; ^cP < 0.05, ^dP < 0.01 LPS.