Identification of osteopontin as the most consistently over-expressed gene in intrahepatic cholangiocarcinoma: Detection by oligonucleotide microarray and real-time PCR analysis

Figure 3 Subclassification of intrahepatic CCC using two-dimensional cluster analysis of 136 different regulated genes/ESTs (dysregulation in more than 70% of all probes, fold change of genetic expression > 2. 0; Pearson's correlation) in relation to histopathological findings (well to poor differentiated tumor tissue). Horizontal lines show all dysregulated genes in one singular tumor tissue probe, vertical lines show the expression of one gene in all analyzed G1-, G2- and G3-tumors. Overexpressed genes are coloured red, downregulated genes are shown in green).