Identification of osteopontin as the most consistently over-expressed gene in intrahepatic cholangiocarcinoma: Detection by oligonucleotide microarray and real-time PCR analysis

Figure 1 A: HE staining of infiltrative intrahepatic cholangiocarcinoma (Patient No. 6; left tumor tissue with cells of a moderate (G2) differentiated adenocarcinoma, right non-malignant liver tissue); B: Detection of cytokeratin 7 in intrahepatic cholangiocarcinoma (same patient as in A) using immunohistochemistry. Cytokeratin 7 was detected in over 80% of all analyzed CCCs strongly overexpressed (14.6-fold change).