Hepatoprotective activity of Sapindus mukorossi and Rheum emodi extracts: In vitro and in vivo studies

Table 3 Effect of S. mukorossi and R. emodi extracts on serum biochemical parameters against CCl₄ induced hepatic injury in rats (Curative study, mean ± SE)

Treatment	Dose (mg/kg, p.o.)	Serum parameters
		ALT (IU/L)	AST (IU/L)	ALP (IU/L)	Bilirubin (mg)
Vehicle control	-	127.73 ± 10.65	100.26 ± 11.50	40.11 ± 2.20	0.11 ± 0.02
Vehicle + CCl4	-	1142.36 ± 80.97	833.59 ± 34.85	64.06 ± 3.00	0.82 ± 0.08
S. mukorossi CCl4 +	2.5	524.18 ± 86.30b	408.72 ± 40.07a	47.38 ± 1.02b	0.40 ± 0.02b
R. emodi CCl4 +	3	384.69 ± 44.39b	314.90 ± 44.41b	49.00 ± 2.19	0.32 ± 0.02b
Silymarin CCl4 +	50	563.47 ± 49.22b	421.54 ± 30.82b	47.96 ± 2.49b	0.42 ± 0.02b

^aP < 0.05,

^bP < 0.01 vs control.