Hepatoprotective activity of Sapindus mukorossi and Rheum emodi extracts: In vitro and in vivo studies

Table 1 In vitro cytotoxicity profile of extracts of S. mukorossi and R. emodi (mean ± SE)

Sample identity	Test concen (&mgr;g/mL)	Cytotoxicity (% release of enzyme in the medium)
		LDH		GPT
		Sp. activity	%leakage	Sp. activity	%leakage
Control	-	5.05 ± 0.22	-	103 ± 2.5	-
S. mukorossi	10	5.00 ± 2.21	NS	111 ± 2.4	NS
	50	4.97 ± 0.23	NS	108 ± 3.1	NS
	100	5.18 ± 0.31	NS	100 ± 1.9	NS
R. emodi	10	5.03 ± 0.11	NS	119 ± 2.0	NS
	50	5.12 ± 0.17	NS	107 ± 2.5	NS
	100	5.08 ± 0.14	NS	114 ± 2.3	NS

NS: Non-significant (t-test).