Copyright
©2008 The WJG Press and Baishideng.
World J Gastroenterol. Apr 28, 2008; 14(16): 2556-2560
Published online Apr 28, 2008. doi: 10.3748/wjg.14.2556
Published online Apr 28, 2008. doi: 10.3748/wjg.14.2556
d 4-sham | d 4-BO | d 10-sham | BOD | d 10-BO | |
Serum total bilirubin (mg/dL) | 0.12 ± 0.04 | 10.54 ± 3.54a | 0.12 ± 0.04 | 0.16 ± 0.05e | 11.18 ± 1.03 |
Serum ALT (U/L) | 36.6 ± 5.7 | 119.6 ± 50.1a | 37.4 ± 3.9 | 2.5 ± 7.3e | 88.8 ± 11.78 |
Total CYP content (nmol/mg MS protein) | 0.577 ± 0.029 | 0.378 ± 0.012a | 0.668 ± 0.080 | 0.603 ± 0.080e | 0.329 ± 0.05 |
Aniline 4-hydroxylation (nmol/mg MS protein/min) | 0.527 ± 0.054 | 0.261 ± 0.026a | 0.568 ± 0.068 | 0.570 ± 0.091e | 0.252 ± 0.03 |
Aminophylline N-demethylation (nmol/mg MS protein/min) | 7.13 ± 0.61 | 2.83 ± 0.50a | 7.88 ± 1.81 | 5.82 ± 1.00c | 2.510 ± 0.23 |
7-ethoxycoumarin O- demethylation (pmol/mg MS protein/min) | 104.4 ± 14.0 | 68.9 ± 20.5a | 123.0 ± 23.8 | 113.7 ± 22.9e | 64.1 ± 4.23 |
- Citation: Fukushima S, Okuno H, Shibatani N, Nakahashi Y, Seki T, Okazaki K. Effect of biliary obstruction and internal biliary drainage on hepatic cytochrome P450 isozymes in rats. World J Gastroenterol 2008; 14(16): 2556-2560
- URL: https://www.wjgnet.com/1007-9327/full/v14/i16/2556.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.2556