Prognostic factors for progression of liver structural lesions in chronic hepatitis C patients

Table 2 Univariate analysis of factors associated with presence of significant hepatic disease according to liver biopsy in patients with chronic HCV infection

Variables	Odds ratio	95% CI	P
Age at first biopsy (yr)	1.0853	1.0370-1.1357	0.001
Duration of infection	1.0593	1.0198-1.1004	0.003
Gender	1.2719	0.5553-2.9132	0.569
Illegal drug use	0.6639	0.2241-1.9666	0.460
Blood transfusion	0.5792	0.2525-1.3284	0.197
ALT	1.2000	0.9808-1.4682	0.076
AST	1.4133	0.9681-2.0633	0.073
GGT	1.2978	0.8178-2.0594	0.268
Albumin	0.3660	0.1556-0.8604	0.021
Prothrombin activity	0.9252	0.8797-0.9730	0.003
Platelets	0.9999	0.9999-1.0000	0.107
Steatosis	1.8571	0.8110-4.2525	0.143
Lymphoid aggregates	3.9747	1.6612-9.5081	0.002
Ductal injury	1.9523	0.4574-8.3329	0.366
Siderosis	9.5454	2.0376-44.7150	0.004
IFN receptors	0.4285	0.1679-1.0938	0.076
Infection duration	0.9975	0.9606-1.0358	0.898