Stronger inhibition of gastric acid secretion by lafutidine, a novel H2 receptor antagonist, than by the proton pump inhibitor lansoprazole

Figure 2 Plasma drug concentrations during a 6 h post administration period in four individuals (No. 1, 4, 5, 6). The solid line (•) indicates the plasma drug concentration after the administration of 10 mg lafutidine, and the broken line (▪) that after the administration of 30 mg LPZ. Lafutidine (T_max 1 h) reached its peak plasma concentration faster than LPZ (T_max 2 h). Arrow: Drug administration.