Anti-sense oligonucleotide labeled with technetium-99m using hydrazinonictinamide derivative and N-hydroxysuccinimidyl S-acetylmercaptoacetyltriglycline: A comparison of radiochemical behaviors and biological properties

Figure 2 Synthesis of NHS-MAG₃. S-acetylthioglycolic acid N-hydroxysuccinimide ester (SATA) was initially synthesized from acetic acid. S-acetyl MAG₃ was obtained by the reaction of SATA and triglycine. NHS-MAG₃ was produced with the coupling of S-acetyl MAG₃ and N-hydroxybudityrylimine.