Effect of Oxymatrine on the TGFbeta-Smad signaling pathway in rats with CCl4-induced hepatic fibrosis

doi:10.3748/wjg.14.2100

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Apr 7, 2008 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2008; 14(13): 2100-2105
Published online Apr 7, 2008. doi: 10.3748/wjg.14.2100

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Figure 2 Expression of Smad 7 protein in liver tissue of model rats was increased when detected with immunohistochemistry ( A: IH, × 200) when compared to the control group. However, the expression of Smad 7 protein in the livers of the Oxymatrine-treated group was even more significantly increased ( B: IH, × 200). The positive rate of Smad 7 protein expression was 1.9% and 4.3% in the model group and the treated group, respectively (data obtained from statistical software, P < 0.05).

Citation: Wu XL, Zeng WZ, Jiang MD, Qin JP, Xu H. Effect of Oxymatrine on the TGFbeta-Smad signaling pathway in rats with CCl₄-induced hepatic fibrosis. World J Gastroenterol 2008; 14(13): 2100-2105
URL: https://www.wjgnet.com/1007-9327/full/v14/i13/2100.htm
DOI: https://dx.doi.org/10.3748/wjg.14.2100