Enhancement of CD4+ T cell activities and modulation of Th1/Th2 lineage development in radiated tumor-bearing rats treated with male zooid of Antheraea pernyi extracts

Table 4 Effect of MZAPE on Th1 and Th2 cytokines (n = 20, mean ± SE) (pg/mL)

	IL-2	P	INF-γ	P	IL-4	P	IL-10	P
Control group	181.99 ± 19.33		89.06 ± 21.44		97.69 ± 7.11		180.14 ± 19.56
Simple irradiation group	129.14 ± 16.96	< 0.001b	74.09 ± 39.29	0.143	100.57 ± 12.01	0.362	179.26 ± 18.13	0.883
Radiation plus	138.16 ± 23.15	< 0.001b	91.25 ± 27.00	0.778	74.78 ± 8.28d	< 0.001bd	180.25 ± 17.32	0.985
MZAPE group
MZAPE group	166.73 ± 13.34d	0.006b	103.85 ± 6.55d	0.005b	66.02 ± 7.14d	< 0.001bd	136.29 ± 18.21d	< 0.001bd
		< 0.001d		0.002d

^bP < 0.001 vs control group;

^dP < 0.001 vs simple irradiation group.