Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3

Table 1 PSC cycle detected by flow cytometry (%)

Group	Medium	G0 + G1 fraction	S phase fraction	G2/M fraction	S + G2/M fraction
1 (Control)	Serum-free medium	89.81	1.94	8.25	10.19
2	Serum-free medium containing 40% SSW	89.63	3.23	7.14	10.37
3	Serum-free medium containing 40% SSW and 1 &mgr;g/mL GAL-3 antibody	89.42	2.70	7.88	10.58
4	Serum-free medium containing 100 ng/mL GAL-3 protein	87.04	3.68	9.28	12.96

Group 1: PSCs exposed to serum-free medium (control group); Group 2: PSCs exposed to serum-free medium containing 40% SSW; Group 3: PSCs exposed to serum-free medium containing 40% SSW and 1 &mgr;g/mL GAL-3 antibody; Group 4: PSCs exposed to serum-free medium containing 100 ng/mL GAL-3 protein.