Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination

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Mar 28, 2008 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2008; 14(12): 1823-1827
Published online Mar 28, 2008. doi: 10.3748/wjg.14.1823

Table 1 β-catenin target genes related to cancer

Function	Target gene
Cell proliferation	C-myc; Cyclin D1
Inhibition of apoptosis	MDR1/PGP; COX-2; PPARδ
Tumor progression	MMPs; uPAR,Upa; CD44; Laminin γ2; Nr-CAM
Growth factors	c-met; VEGF; WISP-1; BMP-4
Transcription factors	c-jun, fra-1; ITF-2; Id2; AF17
Negative feedback targets	Conductin; Tcf-1; Nkd

Citation: Huang D, Du X. Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination. World J Gastroenterol 2008; 14(12): 1823-1827
URL: https://www.wjgnet.com/1007-9327/full/v14/i12/1823.htm
DOI: https://dx.doi.org/10.3748/wjg.14.1823