Herbal compound 861 regulates mRNA expression of collagen synthesis- and degradation-related genes in human hepatic stellate cells

Figure 2 Time course of Cpd 861 on mRNA expressions in LX-2 cells. LX-2 cells were incubated with Cpd 861 (0.01 mg/mL) for 24, 48 and 72 h. The absolute copy number of mRNA for collagen type III, MMP-1, MMP-2, and TIMP-1 was determined by real-time PCR. The data represent mean ± SE of triplicate for each treatment. ^aP < 0.05 and ^bP < 0.01 vs LX-2 cell controls.