Herbal compound 861 regulates mRNA expression of collagen synthesis- and degradation-related genes in human hepatic stellate cells

Figure 1 mRNA expression changes of collagen typesIand III, MMP-1, MMP-2, TIMP-1, and TGF-β1 in LX-2 cells after 48 h of treatment with Cpd 861 (0. 01 g/L) or interferon-γ (1 000 000 U/L). The levels of mRNA were determined by real-time PCR and normalized by GAPDH. Results are expressed as fold inductions compared to each control group. The data represent mean ± SE of triplicate for each treatment.