Aberrant activation of nuclear factor of activated T cell 2 in lamina propria mononuclear cells in ulcerative colitis

Figure 3 Confocal microscopy demonstrating the subcellular distribution of NFAT2 in LMPCs of colon mucosa. A-C are derived from normal colon mucosa, while D-F from UC affected mucosa, G-I from CD affected mucosa. A, D, G represent the detection for NFAT2; B, E, H: The nuclei using DAPI; C, F ,I : the merged images for A, B, D, E, G and H, respectively. Of interest, co-localization of NFAT2 with nuclei is noted in the colonic mucosa of UC (F), but not in CD (I), though there is a heavy infiltration of LMPCs in the CD affected colonic mucosa.