Cyclooxygenase 2 polymorphism and colorectal cancer: -765G>C variant modifies risk associated with smoking and body mass index

Table 1 Characteristics of cases and controls

	Controls/cases	OR 95% CI
Sex
Male	101/70	1
Female	98/67	0.986 (0.638-1.524)
Age (yr)
≤ 60	98/60	1
> 60	101/77	1.245 (0.804-1.928)
Smoking status
Non-smoker	147/75	1
Smoker	52/62	2.337 (1.473-3.708)b
Alcohol duration (yr)
Never	168/103	1
1-15	16/14	1.427 (0.669-3.046)
> 15	15/20	2.175 (1.066-4.437)
Body mass index (kg/m2)
18.5-22.9	101/35	1
23-24.9	38/54	4.101 (2.329-7.220)
> 25	60/48	2.309 (1.345-3.962)d

^bP < 0.001 vs non-smoker group (two-sided χ² test):

^dP < 0.001 vs normal BMI group (two-sided χ² test).