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Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Mar 21, 2008; 14(11): 1774-1780
Published online Mar 21, 2008. doi: 10.3748/wjg.14.1774
Table 1 Characteristics of 195 patients with cirrhosis undergoing surgical procedures under general anesthesia
Total (n =195)Death or decompensation
P valueOdds ratio
No (n = 163)Yes (n = 32)
Mean age (yr)57.1 ± 11.257.2 ± 10.956.5 ± 12.50.73
Gender, n (%)
Female79 (40.5)65 (39.9)14 (43.8)
Male116 (59.5)98 (60.1)18 (56.3)0.68
Ethnicity, n (%)
White159 (81.5)135 (82.8)24 (75.0)
African American27 (13.8)20 (12.3)7 (21.9)0.32
Other9 (4.6)8 (4.9)1 (3.1)
Etiology, n (%)
Hepatitis C73 (37.4)61 (37.2)12 (37.5)0.99
Cryptogenic51 (26.2)43 (26.4)8 (25.0)0.87
Alcohol35 (17.9)26 (16.0)9 (28.1)0.1
Hepatitis B7 (3.6)7 (4.3)0 (0.0)-
Autoimmune hepatitis5 (2.6)5 (3.1)0 (0.0)-
Primary sclerosing cholangitis5 (2.6)4 (2.5)1 (3.1)-
Primary biliary cirrhosis4 (2.1)4 (2.5)0 (0.0)-
A1 antitrypsin deficiency3 (1.5)3 (1.8)0 (0.0)-
Non-alcoholic steatohepatitis2 (1.0)2 (1.2)0 (0.0)-
Amyloidosis2 (1.0)2 (1.2)0 (0.0)-
Hemochromatosis1 (0.5)1 (0.6)0 (0.0)-
Cardiac cirrhosis1 (0.5)1 (0.6)0 (0.0)-
Cystic fibrosis1 (0.5)0 (0.0)1 (3.1)-
Unknown5 (2.6)4 (2.4)1 (3.1)-
Mean CTP score ± SD8.0 ± 1.97.8 ± 1.89.1 ± 1.90.00058
CTP class n (%)
A41 (21.0)40 (24.5)1 (3.1)1
B115 (59.0)95 (58.3)20 (62.5)0.00188.42
C39 (20.0)28 (17.2)11 (34.4)15.71
Mean MELD score ± SD14.2 ± 6.313.2 ± 5.219.1 ± 5.2< 0.0001
MELD score (Tertile)
6-11 (T1)77 (47.2)6 (18.8)1
12-15 (T2)46 (28.2)10 (31.3)0.00082.79
16-40 (T3)40 (24.5)16 (50.0)5.13
Surgery sites
Gastrointestinal101 (51.8)84 (51.5)17 (53.1)0.87
Cardiovascular and thoracic28 (14.4)22 (13.5)6 (18.8)0.42
Genitourinary24 (12.3)22 (13.5)2 (6.3)0.38
Orthopedic24 (12.3)20 (12.3)4 (12.5)-
Head and neck18 (9.2)15 (9.2)3 (9.4)-
Surgery type
Urgent57 (29.2)36 (22.1)21 (65.6)
Elective138 (70.8)127 (77.9)11 (34.4)< 0.0001