Gastric juice for the diagnosis of H pylori infection in patients on proton pump inhibitors

Table 3 Comparison of gastric juice PCR and histology with and without PPI using gastric biopsy PCR as the gold standard

	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Likelihood ratio LR+	Likelihood ratio LR-	Accuracy (%)
Over all (n = 85)
Histology	77	92	98	43	9.6	0.25	80
Gastric juice PCR	87	77	95	53	3.7	0.16	85
On PPI (n = 37)
Histology	73	100	100	14	0.6	2.7	74
Gastric juice PCR	86	100	100	29	9.5	1.4	86
No PPI (n = 48)
Histology	89	90	97	71	0.89	0.12	85
Gastric juice PCR	89	72	91	67	3.17	0.15	85