Gastric juice for the diagnosis of H pylori infection in patients on proton pump inhibitors

Table 2 Comparison of gastric juice PCR and histology using gastric biopsy PCR as the gold standard n (%)

	PCR of gastric biopsy		P value
Over all (n = 85)
Histology	Positive	Negative
Positive	56 (78)	1 (8)	< 0.001
Negative	16 (22)	12 (92)
Gastric juice PCR
Positive	63 (87)	3 (23)	< 0.001
Negative	9 (13)	10 (77)
On PPI (n = 37)
Histology
Positive	23 (66)	0	0.17
Negative	12 (34)	2 (100)
Gastric juice PCR
Positive	30 (86)	0	0.003
Negative	5 (14)	2 (100)
No PPI (n = 48)
Histology
Positive	33 (89)	1 (9)	< 0.001
Negative	4 (11)	10 (91)
Gastric juice PCR
Positive	33 (89)	3 (27)	< 0.001
Negative	4 (11)	8 (73)