Staging accuracy of esophageal cancer by endoscopic ultrasound: A meta-analysis and systematic review

Table 4 Accuracy of EUS with CIs to stage esophageal cancer over the past two decades

	Year	No. of studies	Pooled sensitivity (%)	Pooled specificity (%)	Pooled LR+	Pooled LR-	Pooled DOR
T1	1986-1944	17	80.4 (75.2-84.8)	99.2 (98.4-99.7)	41.5 (6.1-283.3)	0.25 (0.14-0.43)	181.9 (60.7-545.7)
	1995-1999	11	83.9 (76.0-90.0)	99.4 (98.4-99.8)	36.4 (18.5-71.6)	0.21 (0.09-0.47)	299.9 (107.8-834.1)
	2000-2006	8	82.4 (72.6-89.8)	100.0 (99.1-100.0)	59.5 (22.0-161.1)	0.27 (0.16-0.47)	261.2 (81.4-838.0)
T2	1986-1994	17	85.2 (80.2-89.4)	96.8 (95.5-97.8)	18.6 (5.9-58.6)	0.19 (0.12-0.30)	123.9 (47.7-322.0)
	1995-1999	13	86.8 (79.7-92.1)	97.4 (95.8-98.5)	16.9 (9.1-31.1)	0.20 (0.11-0.38)	139.5 (56.6-343.8)
	2000-2006	8	62.9 (52.0-72.9)	93.4 (90.4-95.6)	8.3 (4.3-15.9)	0.47 (0.34-0.64)	24.7 (9.1-67.4)
T3	1986-1994	18	90.8 (88.1-93.0)	94.6 (92.6-96.2)	13.9 (5.2-36.9)	0.12 (0.07-0.19)	157.7 (70.9-351.1)
	1995-1999	14	93.7 (90.0-96.3)	96.4 (94.5-97.7)	12.6 (7.6-20.9)	0.11 (0.08-0.17)	159.4 (77.9-326.2)
	2000-2006	8	89.9 (84.5-93.9)	90.0 (86.1-93.2)	7.0 (4.6-10.8)	0.11 (0.04-0.32)	100.9 (33.5-303.9)
T4	1986-1994	18	92.1 (87.9-95.2)	96.9 (95.6-97.9)	24.7 (8.4-72.7)	0.09 (0.04-0.23)	278.8 (97.2-799.9)
	1995-1999	14	89.2 (79.8-95.2)	98.0 (96.7-98.96)	22.2 (13.2-37.3)	0.23 (0.15-0.36)	227.1 (89.7-575.0)
	2000-2006	8	100.0 (91.8-100.0)	97.5 (95.4-98.8)	20.2 (8.8-46.3)	0.11 (0.04-0.29)	272.6 (73.4-1013.2)
N	1986-1994	17	88.0 (85.4-90.2)	85.2 (83.4-86.9)	3.6 (2.4-5.4)	0.2 (0.1-0.3)	27.6 (14.6-52.4)
	1995-1999	17	82.6 (78.0-85.9)	84.4 (81.6-86.9)	3.0 (2.1-4.5)	0.3 (0.2-0.4)	14.8 (7.5-29.3)
	2000-2005	10	81.6 (77.8-85.1)	82.4 (78.2-86.1)	3.4 (2.2-5.3)	0.3 (0.2-0.4)	14.9 (6.7-33.1)