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©2008 The WJG Press and Baishideng.
Figure 2 Antiproliferative effects of sorafenib-based combination treatment.
A: Huh-7 and B: HEP-G2 cells were treated for 72 h with sub-IC50 concentrations of sorafenib and the histone deactylase inhibitor MS-275. Combination of both agents resulted in synergistic growth inhibition of Huh-7 cells, while rather additive growth inhibitory effects were observed in HepP-G2 cells (mean ± SEM).
- Citation: Höpfner M, Schuppan D, Scherübl H. Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer. World J Gastroenterol 2008; 14(1): 1-14
- URL: https://www.wjgnet.com/1007-9327/full/v14/i1/1.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.1