Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump

Table 5 1331T>C (V444A): Fisher’s exact test and ORs for the presence of homozygous CC variant and the C allele in the different groups

	CC vs TT			C vs T
	Fisher	Odds ratio	95% CI	Fisher	Odds ratio	95% CI
ICPoldvs Pregnant controls	0.0041	nd1	-	0.0004	4.8	2.2-15.0
ICPoldvs Caucasian controls	0.0029	nd1	-	0.0005	3.8	1.9-11.1
ICPnewvs Pregnant controls	0.1082	4.4	0.7-27.2	0.0441	2.1	1.0-4.7
ICnewvs Caucasian controls	0.1461	2.9	0.6-13.8	0.0850	1.7	0.9-3.4
ICPtotalvs Pregnant controls	0.0065	10.5	1.9-63.7	0.0007	3.0	1.7-6.4
ICPtotalvs Caucasian controls	0.0025	6.9	1.6-32.1	0.0006	2.4	1.5-4.5

¹Could not be determined, as TT = 0.