Anaplastic carcinoma associated with a mucinous cystic neoplasm of the pancreas during pregnancy: Report of a case and a review of the literature

Table 2 Reported cases of anaplastic carcinoma occuring in association with MCNs

No	Author (reference)	Case (age/sex)	Diagnosis	Anaplastic carcinoma								Outcome (survival time)
				Tumorlocation	Size (cm)	Spindle cell	Giant cell	Adeno-carcinoma	Invasion	lymphatic involvement	Distant metastasis
1	Compagno J[3]	32/F	Anaplastic carcinoma derived from MCN	Body	ND	ND	ND	+	ND	ND	-	Dead (3 yr)
2	Gracia Rego JA[4]	45/F	Mucinous cystadenocarcinoma with pseudosarcomatous mural nodules	Body-tail	11	+	ND	+	Capsule	ND	-	Dead (16 mo)
3	Hartz PH[5]	56/F	Cystadenocarcinoma with anaplasia	Tail	6	+	+	ND	Capsule, peripan-creatic nerve	ND	Liver, peri-toneum	Dead (autopsy)
4	Lane RB[6]	25/F	Anaplastic carcinoma with MCN	Tail, liver, lymph node	15	+	-	+	ND	+	Liver	ND
5	Logan SE[7]	23/F	Pleomorhic adenocarcinoma originated from MCN	Body-tail	17	+	ND	+	Stomach	+	Liver	Dead (1 mo)
6	Marinho A[8]	70/F	Mucinous cystadenocarcinoma with a mural nodule of anaplastic carcinoma	Body-tail	4.5	ND	ND	+	Capsule	ND	-	ND
7	Sommers SC[9]	48/M	Cystadenocarcinoma with foci of pleomorphic carcinoma	ND	ND	ND	+	+	ND	+	-	Dead (6 mo)
8	Tsujimura T[11]	43/F	Malignant histiocytoma with mucinous cystadenoma	Tail	16	+	+	ND	ND	ND	-	ND
9	1WenigBM[12]	67/M	MCN with sarcoma stroma	Tail	19	+	ND	+	ND	ND	ND	Dead (15 mo)
10	1Wenig BM[12]	48/F	MCN with sarcoma stroma	Tail	ND	+	ND	+	ND	ND	ND	Alive (12 mo)
11	1Wenig BM[12]	65/F	MCN with sarcoma stroma	Tail, peritoneum	30	+	ND	+	Vascular	ND	Omentum, pleura	Dead (9 mo)
12	Hakamada K	39/F	Anaplastic carcinoma with recurrent MCN, borderline-type	Tail	5	+	+	+	-	-	-	Alive (4 yr)

ND: Not described; MCN: Mucinous cystic neoplasm.

¹Later re-analyzed genetically and reported by van den Berg W[11].