Towards a multiscale model of colorectal cancer

doi:10.3748/wjg.v13.i9.1399

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Mar 7, 2007 (publication date) through Dec 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2007; 13(9): 1399-1407
Published online Mar 7, 2007. doi: 10.3748/wjg.v13.i9.1399

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Figure 6 Schematic of the biomechanical model developed in Edwards and Chapman[44]. Proliferation in the epithelium generates stress within the layer through cellular attachment to the underlying basal lamina. For certain choices of the model parameters, the stress that is generated causes the layer to buckle, inducing a displacement y and initiating crypt budding and fission.

Citation: van Leeuwen IM, Edwards CM, Ilyas M, Byrne HM. Towards a multiscale model of colorectal cancer. World J Gastroenterol 2007; 13(9): 1399-1407
URL: https://www.wjgnet.com/1007-9327/full/v13/i9/1399.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i9.1399