Tetrandrine stimulates the apoptosis of hepatic stellate cells and ameliorates development of fibrosis in a thioacetamide rat model

Figure 5 Representative liver section showing reaction of alpha-smooth muscle cell like actin (α-SMA) with mouse anti-α-SMA monoclonal antibody. α-SMA immunoreactivity (arrows) was seen in stellate cells in the fibrotic area. A: normal group; B: control group; C: TAA group with tetrandrine (5 mg/kg); D: TAA group with tetrandrine (10 mg/kg); E: TAA group with tetrandrine (20 mg/kg); F: TAA group with interferon-г (5 × 10⁴ U).