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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2007; 13(8): 1221-1229
Published online Feb 28, 2007. doi: 10.3748/wjg.v13.i8.1221
Published online Feb 28, 2007. doi: 10.3748/wjg.v13.i8.1221
Table 6 Genotype-phenotype correlation in UC patients evaluated by comparison of carriers vs non-carriers of at least one CARD15 variant (CARD15+), the AA/AG genotypes of DLG5 variant (DLG5+), and presence of TC haplotype of OCTN1/2 variants (TC+)
| UC n = 186 | CARD15+(n = 36) | CARD15-(n = 148) | DLG5+(n = 27) | DLG5-(n = 144) | OCTNTC haplotype (%) | |
| + | - | |||||
| Localization UC, n (%) | ||||||
| Rectum-sigmoid | 7 (19) | 36 (24) | 9 (33) | 28 (19) | 45 | 55 |
| Left colon | 11 (31) | 43 (29) | 6 (22) | 44 (31) | 44 | 56 |
| Pancolitis | 18 (50) | 69 (47) | 12 (45) | 72 (50) | 47 | 53 |
| Growth delay y/n, (%) | 3/26 (10) | 18/98 (16) | 5/14 (26) | 16/101 (14) | 43/46 | 57/54 |
| Resective surgery y/n, (%) | 4/32 (11) | 9/139 (6) | 1/26 (4) | 9/135 (6) | 31/46 | 69/54 |
| EIM y/n, (%) | 9/27 (25) | 37/111 (25) | 4/23 (15) | 40/104 (28) | 51/44 | 49/56 |
| ASCA (pos/neg), (%) | 4/10 (29) | 14/46 (23) | 5/10 (33) | 13/46 (22) | 42/46 | 58/54 |
| ANCA (pos/neg), (%) | 13/6 (68) | 52/43 (55) | 11/8 (58) | 52/40 (57) | 43/40 | 57/60 |
| Steroids need, y/n, (%) | 26/10 (72) | 109/39 (74) | 21/6 (78) | 105/39 (73) | 46/46 | 54/54 |
- Citation: Cucchiara S, Latiano A, Palmieri O, Staiano A, D’Incà R, Guariso G, Vieni G, Rutigliano V, Borrelli O, Valvano M, Annese V. Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases. World J Gastroenterol 2007; 13(8): 1221-1229
- URL: https://www.wjgnet.com/1007-9327/full/v13/i8/1221.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i8.1221