Copyright
©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2007; 13(8): 1221-1229
Published online Feb 28, 2007. doi: 10.3748/wjg.v13.i8.1221
Published online Feb 28, 2007. doi: 10.3748/wjg.v13.i8.1221
Table 3 Genotype distributions of CARD15, OCTN1-2, DLG5 genes, and IBD5 locus polymorphisms
| SNPs | Genotype | Crohn’sdisease | P valueOR 95% IC | Controls | P valueOR 95% IC | Ulcerativecolitis |
| CARD15 R702W | TT | TT and CT vs CC | 0 (0) | |||
| 5 (3) | P < 0.001 | 1 (0) | NS | |||
| CT | 38 (19) | 3.47 (2.06-5.86) | 25 (7) | 17 (9) | ||
| CC | 153 (78) | 321 (93) | 167 (91) | |||
| G908R | CC | 2 (1) | CC and CG vs GG | 0 (0) | NS | 1 (1) |
| CG | 25 (13) | P < 0.001 | 18 (5) | 12 (7) | ||
| GG | 170 (86) | 2.90 (1.55-5.42) | 329 (95) | 171 (93) | ||
| 1007fsInsC | CC | 1 (1) | CC and CG vs GG | 0 (0) | NS | 0 (0) |
| CG | 25 (13) | P = 0.0005 | 11 (3) | 10 (5) | ||
| GG | 172 (87) | 4.62 (2.23-9.57) | 336 (97) | 176 (95) | ||
| OCTN1/2 C1672T | TT | 42 (24) | TT vs CT and CC | 57 (16) | P = 0.10 | 36 (22) |
| CT | 79 (46) | P = 0.03 | 178 (51) | 76 (47) | ||
| CC | 52 (30) | 1.63 (1.04-2.56) | 112 (32) | 49 (30) | ||
| -G207C | CC | 50 (29) | CC vs CG and GG | 72 (21) | P = 0.05 | 46 (29) |
| CG | 84 (49) | P = 0.035 | 183 (53) | 77 (48) | ||
| GG | 38 (22) | 1.57 (1.03-2.38) | 92 (27) | 38 (24) | ||
| IBD5 IGR2198a_1 | GG | 40 (21) | GG vs CG and CC | 55 (16) | P = 0.09 | 39 (22) |
| CG | 93 (49) | P = 0.13 | 175 (50) | 86 (48) | ||
| CC | 58 (30) | 117 (34) | 54 (30) | |||
| IGR2096a_1 | AA | 44 (23) | AA vs AC and CC | 50 (14) | NS | 32 (18) |
| AC | 89 (47) | P = 0.01 | 176 (51) | 91 (51) | ||
| CC | 58 (30) | 1.78 (1.13-2.79) | 121 (35) | 56 (31) | ||
| DLG5 113G/A | AA | 1 (1) | NS | 2 (1) | NS | 1 (1) |
| AG | 16 (10) | 57 (16) | 26 (15) | |||
| GG | 148 (90) | 288 (83) | 144 (84) |
- Citation: Cucchiara S, Latiano A, Palmieri O, Staiano A, D’Incà R, Guariso G, Vieni G, Rutigliano V, Borrelli O, Valvano M, Annese V. Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases. World J Gastroenterol 2007; 13(8): 1221-1229
- URL: https://www.wjgnet.com/1007-9327/full/v13/i8/1221.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i8.1221