Aqueous suspension of anise &ldquo;Pimpinella anisum&rdquo; protects rats against chemically induced gastric ulcers

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Feb 21, 2007 (publication date) through Feb 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2007; 13(7): 1112-1118
Published online Feb 21, 2007. doi: 10.3748/wjg.v13.i7.1112

Table 2 Effect of aqueous anise suspension on ethanol-induced histopathological changes in rat stomach

Groupserial	Treatment and dose(mg/kg, body weight/day)	Histopathological changes
Groupserial	Treatment and dose(mg/kg, body weight/day)	Congestion	Haemorrhage	Edema	Necrosis	Inflammatorychanges	Dysplasticchanges	Erosions	Ulceration
1	Control (distilled water)	-	-	-	-	-	-	-	-
	(1 mL/rat)
2	Ethanol, 80% (1 mL/rat)	++	+++	++	++	+	+	+++	+
3	Pimpinella anisum	+	+	+	-	-	-	+	-
	(250) + ethanol, 80% (1 mL/rat)
4	Pimpinella anisum	+	+	+	-	-	-	+	-
	(500) + ethanol, 80% (1 mL/rat)

-: normal, +: moderate, ++: severe, +++: intensely severe.

Citation: Al Mofleh IA, Alhaider AA, Mossa JS, Al-Soohaibani MO, Rafatullah S. Aqueous suspension of anise “Pimpinella anisum” protects rats against chemically induced gastric ulcers. World J Gastroenterol 2007; 13(7): 1112-1118
URL: https://www.wjgnet.com/1007-9327/full/v13/i7/1112.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i7.1112