Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells

Figure 3 Immunofluorescence for cell localization of the p65 NF-κB subunit. Cellular compartmentation of the p65 NF-κB subunit was examined in KMCH cells by confocal laser scanning microscopy. The p65 NFκB subunit was completely cytoplasmic in untreated KMCH cholangiocarcinoma cells; its localization also remained cytoplasmic following exposure to MG132 (1 μmol/L) for 24 h.