Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray

Table 7 β-catenin and c-myc status in relation to clinicopathological data

Clinicopathological	parameters	Total	β-caternin		P	c-myc		P
			-	+		-	+
Age	< 58	39	6	33	0.9831	9	29	0.1171
	≥ 58	46	7	39		5	41
Gender	Male	48	8	40	0.6891	10	38	0.2371
	Female	37	5	32		4	32
Histological grade	Low	24	10	14		11	13
	Moderate	50	3	47	0.0002	3	46	0.0002
	High	11	0	11		0	11
Lymph node metastasis	Negative	53	4	49	0.0111	4	48	0.0051
	Positive	32	9	23		10	22
Distant metastasis	Negative	71	8	63	0.0201	6	65	0.0001
	Positive	14	5	9		8	5
Dukes stage	A	15	0	15		0	15
	B	33	2	31	0.0082	2	31	0.0002
	C	23	6	17		4	19
	D	14	5	9		8	5

¹Chi-square test;

²Fisher’s exact test.