New anti-proliferative agent, MK615, from Japanese apricot &ldquo;Prunus mume&rdquo; induces striking autophagy in colon cancer cells in vitro

doi:10.3748/wjg.v13.i48.6512

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Dec 28, 2007 (publication date) through Feb 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Dec 28, 2007; 13(48): 6512-6517
Published online Dec 28, 2007. doi: 10.3748/wjg.v13.i48.6512

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Figure 5 Electron micrographs of autophagy induced by MK615. A: MK615 induced typical features of apoptosis in SW480 cells; B-F: Autophagy induced by MK615. Cytoplasmic vacuoles (autophagosomes) induced by MK615 in SW480 B and C, COLO D and E and WiDr (F) cells. Degenerated mitochondria are evident (arrows in E and F).

Citation: Mori S, Sawada T, Okada T, Ohsawa T, Adachi M, Keiichi K. New anti-proliferative agent, MK615, from Japanese apricot “Prunus mume” induces striking autophagy in colon cancer cells in vitro. World J Gastroenterol 2007; 13(48): 6512-6517
URL: https://www.wjgnet.com/1007-9327/full/v13/i48/6512.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i48.6512