Imatinib-induced fatal acute liver failure

Table 1 Laboratory values

Date	AST	ALT	ALP	TB	DB	WBC	Neu	PT (%)
29/12/5	70	55	197	0.5	0.14	247	148.2
21/2/6	9	13	330	0.3	0.08	5.78	4.769
10/5/6	38	49	204	0.47	0.1
31/5/6	1060	1493	288	0.68	0.2
14/6/6	2224	3185	648	8.43	5.45
16/6/6	2595	3028	668	12.19	7.65			30
21/6/6	1887	1941	831	25.4	19.81	9.86	7.701	13
22/6/6	1626	1757	756	26	20.28	9.47	7.59	11
23/6/6	1495	1752	793	27	20.79	10	7.36	9
24/6/6	1467	1767	800	26.8	21.44	14.4	11.16	9
25/6/6	1359	1553	789	32	23.36	17	12.75	6
26/6/6	1212	1121	774	36	26.64	22.2	17.1	6
27/6/6	1024	900	686	24.7	9.5	86.8	39.9	N-M1
28/6/6	1269	561	362	11.5	4.8	42	33.6	N-M1

TB: Total bilirubin, n < 12 mg/L; DB: direct bilirubin, n < 3 mg/L; AST: Aspartate aminotransferase, n < 40 IU/L; ALT: Alanine aminotransferase, n < 35 IU/L; ALP: Alkaline phosphatase, n < 240 IU/L; GGT: Gamma-glutamyltransferase, n < 32 IU/L; WBC: White blood cells, n = 4000-10 000 cells/mm³; Neu: Neutrophils, n = 2000-6500 cells/mm³; PT: Prothrombin time, n = 70%-100%;

¹N-M: Non-measurable due to extremely prolonged prothrombin time.