Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model

Table 5 Effect of ALE on sister-chromatid exchange (SCE) frequencies (500 plates/group) in different groups of mice killed at various time points

Weeks after tumour inoculation	Group	MeanSCE/cell	Reduction infrequency (%)
1	EAC control	4.59 ± 0.57	-
	EAC + ALE	3.62 ± 0.29	21.13
2	EAC control	6.89 ± 1.13	-
	EAC + ALE	3.78 ± 0.78a	45.14
3	EAC control	7.83 ± 1.05	-
	EAC + ALE	4.64 ± 0.54b	40.74
4	EAC control	10.26 ± 1.67	-
	EAC + ALE	4.83 ± 0.69c	52.92
5	EAC control	14.94 ± 2.14	-
	EAC + ALE	5.12 ± 1.16d	65.73

Abbreviations: ALE: Aqueous leaf extract of A. ilicifolius; EAC: Ehrlich ascites carcinoma. Values represent mean ± SE (n = 10).

^aP < 0.05,

^bP < 0.02,

^cP < 0.01, and

^dP < 0.001 vs EAC control.