Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model

Table 4 Changes in total count (TC), Hb level and haematocrit in different groups of mice treated with or without ALE

Days following EACcell inoculation	Group	TC (RBC) (106/mm3)	TC (WBC) (106/mm3)	Hb (g%)	Haematocrit (%)
0	Normal control	7.3 ± 0.12	5.8 ± 0.23	12.6 ± 0.16	33.43 ± 0.16
	EAC control	7.2 ± 0.15	6.5 ± 0.52	12.0 ± 0.31	32.16 ± 0.27
	ALE control	7.3 ± 0.14	5.9 ± 0.22	12.5 ± 0.16	33.58 ± 0.25
	EAC + ALE	7.3 ± 0.13	6.2 ± 0.15	12.2 ± 0.27	33.11 ± 0.23
10	Normal control	7.4 ± 0.14	5.8 ± 0.63	12.6 ± 0.65	33.51 ± 0.32
	EAC control	6.6 ± 0.76	10.4 ± 0.72b	10.0 ± 0.78a	25.74 ± 0.53c
	ALE control	7.6 ± 0.18	5.7 ± 0.55	12.8 ± 0.61	33.75 ± 0.35
	EAC + ALE	6.9 ± 0.53	7.7 ± 0.68e	11.0 ± 0.49	29.08 ± 0.69d
20	Normal control	7.3 ± 0.54	5.7 ± 0.43	12.4 ± 0.78	33.46 ± 0.17
	EAC control	5.1 ± 0.67a	13.9 ± 0.56b	8.2 ± 0.92f	21.05 ± 0.26c
	ALE control	7.5 ± 0.51	5.7 ± 0.38	12.6 ± 0.73	33.71 ± 0.18
	EAC + ALE	6.7 ± 0.12	7.9 ± 0.48d	11.5 ± 0.57h	28.87 ± 0.35d
30	Normal control	7.5 ± 0.14	5.8 ± 0.23	12.7 ± 0.84	33.49 ± 0.16
	EAC control	4.3 ± 0.12b	18.8 ± 0.54b	6.4 ± 0.93b	17.63 ± 0.72c
	ALE control	7.7 ± 0.13	5.7 ± 0.24	12.9 ± 0.76	33.65 ± 0.21
	EAC + ALE	7.1 ± 0.13d	8.4 ± 0.71d	12.1 ± 0.77d	30.23 ± 0.57d

Abbreviations: ALE: Aqueous leaf extract of A. ilicifolius; EAC: Ehrlich ascites carcinoma; TC: Total count. Values represent mean ± SE (n = 10).

^aP < 0.02,

^bP < 0.001,

^cP < 0.05, and

^fP < 0.01 vs Normal control.

^dP < 0.001,

^eP < 0.02, and

^hP < 0.01 vs EAC control.