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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2007; 13(48): 6518-6528
Published online Dec 28, 2007. doi: 10.3748/wjg.v13.i48.6518
Published online Dec 28, 2007. doi: 10.3748/wjg.v13.i48.6518
Table 2 Relationship between cryoglobulin-positivity and the presence (%) of extrahepatic manifestations in patients with chronic HCV infection
| Extrahepaticmanifestations | Cryoglobulin-positivepatients (n = 51) | Cryoglobulin-negativepatients (n = 85) | P | Odds ratio(95% confidence interval) |
| Fatigue | 92.2 | 40.0 | 0.000 | 17.6 (5.8-53.4) |
| Purpura | 41.2 | 3.5 | 0.000 | 19.1 (5.3-68.8) |
| Raynaud' phenomenon | 25.5 | 3.5 | 0.000 | 9.3 (2.5-34.7) |
| Arthralgia | 33.3 | 9.4 | 0.001 | 4.8 (1.8-12.2) |
| Paresthesia | 41.2 | 7.1 | 0.000 | 9.2 (3.3-25.0) |
| Renal involvement | 45.1 | 12.4 | 0.000 | 5.5 (2.3-12.7) |
| Type 2 diabetes | 35.3 | 15.3 | 0.011 | 3.0 (1.3-6.8) |
| Lymphadenomegaly | 35.3 | 4.7 | 0.000 | 11.0 (3.4-35.1) |
| Lymphoma | 17.6 | 3.5 | 0.015 | 5.8 (1.5-22.7) |
| Pulmonary fibrosis | 25.5 | 9.4 | 0.015 | 3.2 (1.2-8.6) |
| Thyroid dysfunction | 15.7 | 14.1 | ||
| Xerostomia | 11.8 | 3.5 | ||
| Lichen planus | 7.8 | 4.7 | ||
| Thrombocytopenia | 58.8 | 15.3 | 0.000 | 7.9 (3.5-17.8) |
| ANA | 29.4 | 11.8 | 0.013 | 3.1 (1.2-76.0) |
| ASMA | 33.3 | 7.1 | 0.000 | 6.5 (2.3-18.1) |
| ANCA | 25.5 | 5.9 | 0.002 | 5.4 (1.9-16.4) |
| ACL-antibodies | 17.6 | 3.5 | 0.010 | 5.8 (1.5-22.7) |
- Citation: Stefanova-Petrova DV, Tzvetanska AH, Naumova EJ, Mihailova AP, Hadjiev EA, Dikova RP, Vukov MI, Tchernev KG. Chronic hepatitis C virus infection: Prevalence of extrahepatic manifestations and association with cryoglobulinemia in Bulgarian patients. World J Gastroenterol 2007; 13(48): 6518-6528
- URL: https://www.wjgnet.com/1007-9327/full/v13/i48/6518.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i48.6518