Effect of arsenic trioxide on vascular endothelial cell proliferation and expression of vascular endothelial growth factor receptors Flt-1 and KDR in gastric cancer in nude mice

Table 1 Effect of As₂O₃ on Flt-1 and KDR/Flk-1 expression in tumor xenografts (fluorescence intensity) (n = 10, mean ± SD)

Group	Flt-1	KDR/Flk-1
Control	137.41 ± 3.36	141.62 ± 1.66
2.5 mg/kg	103.53 ± 2.23b	114.99 ± 2.19b
5 mg/kg	72.17 ± 0.87bd	101.11 ± 1.89bd

^bP < 0.001, treatment groups vs control group;

^dP < 0.001, 5 mg/kg group vs 2.5 mg group.