Antitumor and antiangiogenic activities of anti-vascular endothelial growth factor hairpin ribozyme in human hepatocellular carcinoma cell cultures and xenografts

doi:10.3748/wjg.v13.i47.6425

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Dec 21, 2007 (publication date) through Jan 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2007; 13(47): 6425-6432
Published online Dec 21, 2007. doi: 10.3748/wjg.v13.i47.6425

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Figure 2 Effects of anti-hVEGF hairpin ribozyme on expression of VEGF and proliferation of SMMC-7721 cells in vitro. A: ELISA validation of VEGF expression; B: RT-PCR validation of VEGF mRNA transcription in SMMC-7721 group(1), SMMC-7721/pcDNA3.1+ group(2) and SMMC-7721/RZ group(3), (M: DL2000 marker); C: Influence of ribozyme on SMMC-7721 cell proliferation; D: Influence of ribozyme on inhibitory rate for proliferation of SMMC-7721 cells.

Citation: Li LH, Guo ZJ, Yan LL, Yang JC, Xie YF, Sheng WH, Huang ZH, Wang XH. Antitumor and antiangiogenic activities of anti-vascular endothelial growth factor hairpin ribozyme in human hepatocellular carcinoma cell cultures and xenografts. World J Gastroenterol 2007; 13(47): 6425-6432
URL: https://www.wjgnet.com/1007-9327/full/v13/i47/6425.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i47.6425