Intestinal endotoxemia plays a central role in development of hepatopulmonary syndrome in a cirrhotic rat model induced by multiple pathogenic factors

Table 1 Levels of endotoxin, TNF-α, ALT and MDA in plasma and PVP (mean ± SD, n = 6)

Groups	Endotoxin (Eu/mL)	TNF-α (ng/mL)	ALT (u/L)	MDA (nmol/mL)	PVP (H2O cm)
Normal	0.09 ± 0.03	0.53 ± 0.16	5.85 ± 2.24	0.06 ± 0.03	10.31 ± 1.16
4th wk	0.19 ± 0.03a	1.37 ± 0.35a	56.24 ± 14.73a	0.10 ± 0.05	17.54 ± 1.84a
6th wk	0.24 ± 0.04a	1.68 ± 0.23a	53.50 ± 22.10a	0.18 ± 0.03ac	15.44 ± 3.11ac
8th wk	0.31 ± 0.08ae	2.42 ± 0.38ae	219.10 ± 17.37ae	0.26 ± 0.06ae	18.38 ± 2.53ae

^aP < 0.05 vs normal group;

^cP < 0.05 vs 4th wk group;

^eP < 0.05 vs 6th wk group.