Selective decrease in colonic CD56+ T and CD161+ T cells in the inflamed mucosa of patients with ulcerative colitis

Figure 2 Selective decreases in the proportions of CD56⁺CD3⁺ (A) and CD161⁺CD3⁺ (B) cells in inflamed colonic mucosa of patients with UC. Box plot graphical representation of the percentage of colonic NKR⁺ T cells from normal mucosa of non-UC patients (n = 18), uninflamed mucosa (endoscopic Matts’ grade 1, n = 51), and inflamed mucosa (Matts’ grades 2-4, n = 45). ^bP < 0.0001, ^dP < 0.0005; inflamed mucosa vs normal or uninflamed mucosa. (C, D) No relation was observed between the percentage of conventional T cells (CD56^-CD3⁺ or CD161^-CD3⁺ cells) and the degree of endoscopic inflammation.