Comprehensive screening for reg1α gene rules out association with tropical calcific pancreatitis

Table 3 Comparison of reg1α gene polymorphisms in FCPD and TCP patients, and controls

SNP1	Minor allele frequency			FCPD vs TCP		FCPD vs Controls		TCP vs Controls
	FCPD (n = 94)	TCP (n = 101)	Controls (n = 150)	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
G-938A	0.36	0.32	0.33	1.20 (0.64-2.24)	0.55	1.14 (0.61-2.13)	0.66	0.96 (0.51-1.80)	0.88
T-912G	0.47	0.51	0.50	0.85 (0.47-1.54)	0.57	0.89 (0.49-1.60)	0.67	1.04 (0.58-1.88)	0.89
T-385C	0.31	0.30	0.29	1.05 (0.55-2.00)	0.88	1.10 (0.57-2.11)	0.76	1.05 (0.55-2.02)	0.88
T-243G	0.33	0.35	0.35	0.91 (0.49-1.71)	0.77	0.91 (0.49-1.71)	0.77	1.00	1.00
G209T	0.24	0.17	0.17	1.54 (0.73-3.27)	0.22	1.54 (0.73-3.27)	0.22	1.00	1.00
G2199A	0.41	0.33	0.34	1.41 (0.76-2.62)	0.24	1.35 (0.73-2.50)	0.31	0.96 (0.51-1.79)	0.88

SNP: Single nucleotide polymorphism; n: Number of individuals; OR: Odds ratio; CI: Confidence interval; TCP: Tropical calcific pancreatitis; FCPD: Fibrocalculous pancreatic diabetes;

¹Only SNPs with > 3% minor allele frequency have been presented; The minor allele frequency at each polymorphism was compared between the three groups and P value with OR and 95% CI were calculated.