Stability of cirrhotic systemic hemodynamics ensures sufficient splanchnic blood flow after living-donor liver transplantation in adult recipients with liver cirrhosis

Table 2 Clinical profiles before, during and after LDLT

Clinical profile	Group I(n = 25)	Group II(n = 5)	P valuea
Before LDLT
Age	51.8 ± 9.8	58.6 ± 3.5	NS
Body surface area (m2)	1.69 ± 0.18	1.61 ± 0.12	NS
Child-Pugh score (points)	9.2 ± 2.3	10.8 ± 2.2	NS
Model for end-stage liver disease score (points)	17.6 ± 6.7	17.4 ± 7.1	NS
During LDLT
Native liver weight (g)	857.0 ± 227.5	946.0 ± 376.2	NS
Portal venous pressure before removal of native liver (mmHg)	21.5 ± 4.7	24.6 ± 7.1	NS
Cold ischemic time (min)	163.7 ± 79.0	139.6 ± 52.6	NS
Warm ischemic time (min)	55.1 ± 16.7	45.8 ± 12.7	NS
Anhepatic phase (min)	209.2 ± 104.9	184.4 ± 177.6	NS
Operative time (min)	899.4 ± 126.7	933.4 ± 131.0	NS
Blood loss (mL)	22515.7 ± 14200.5	22788.6 ± 19247.8	NS
Graft weight (g)	687.8 ± 124.6	632.0 ± 72.9	NS
Graft-recipient weight ratio	1.09 ± 0.21	1.23 ± 0.37	NS
After LDLT
Intensive care unit stay (d)	5.1 ± 1.9	35.6 ± 15.7	< 0.005
%SLV based on CT volumetry
2 wk after LDLT	1.14 ± 0.22	1.07 ± 0.09	NS
4 wk after LDLT	1.05 ± 0.15	1.17 ± 0.16	NS
LHL15 based on 99mTc-GSA liver scintigraphy
2 wk after LDLT	0.935 ± 0.026	0.846 ± 0.061	< 0.005
4 wk after LDLT	0.941 ± 0.017	0.751 ± 0.034	< 0.005
Histopathological fraft parenchymal damage score (points)
Within 4 wk after LDLT	3.9 ± 1.4	10.6 ± 1.3	< 0.005

Statistical differences between Groups I and II analyzed by Mann-Whitney’s U test (NS: P > 0.05). LDLT: Living-donor liver transplantation; SLV: Standard liver volume; CT: Computed tomographic; LHL15: The ratio of liver to heart-plus-liver radioactivity at 15 min; 99mTc-GSA: Technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin.