New approaches in angiogenic targeting for colorectal cancer

doi:10.3748/wjg.v13.i44.5857

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Nov 28, 2007 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2007; 13(44): 5857-5866
Published online Nov 28, 2007. doi: 10.3748/wjg.v13.i44.5857

Table 3 Trials for Vatalanib with chemotherapy in metastatic CRC

REF	Regimen	Pts	RR (%)	P	PFS or TTP (mo)	P	OS (mo)	P
58	FOLFOX-4	583	46	NS	7.6	0.118	NR	-
	FOLFOX-4 + Vatalanib	585	42	NS	7.7	0.118	NR	-
59-60	FOLFOX-4	429	18	NR	4.1	0.026	11.8	0.511
	FOLFOX-4 + Vatalanib	426	19	NR	5.5	0.026	12.1	0.511

CRC: Colorectal carcinoma; REF: Reference; Pts: Patients enrolled; FOLFOX-4: Oxaliplatin/5-FU/leucovorin; RR: Response rate; PFS: Progression-free survival; TTP: Time to tumor progression; OS: Overall survival; NS: Statistically nonsignificant; NR: Not reported.

Citation: Prat A, Casado E, Cortés J. New approaches in angiogenic targeting for colorectal cancer. World J Gastroenterol 2007; 13(44): 5857-5866
URL: https://www.wjgnet.com/1007-9327/full/v13/i44/5857.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i44.5857