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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 28, 2007; 13(44): 5805-5812
Published online Nov 28, 2007. doi: 10.3748/wjg.v13.i44.5805
Published online Nov 28, 2007. doi: 10.3748/wjg.v13.i44.5805
Table 1 Novel chemoradiation combinations
Chemotherapy | RT (Gy) | GI grade 3-4 toxicity (%) | DS (%) | pCR (%) | ||
Capecitabine (mg/m2 bid) | ||||||
Kim et al | 825 d 1-14 and 22 - 35 | 50.4 | - | 84 | 31 | |
De Paoli et al | 825 bid continuous | 50.4 | - | 57 | 24 | |
5-FU (mg/m2 CI) | CPT-11 (mg/m2 weekly) | |||||
Mehta et al | 200 | 50 | 50.4 | 28 | 71 | 37 |
Klautke et al | 250 | 40 | 50.4 | 32 | 76 | 24 |
Mohiuddin et al | Arm 1: 225 | Arm 1: - | HART: 55.2-60 | 27 | 78 | 26 |
Arm 2: 225 | Arm 2: 50 | 50-54 | 37 | 78 | 26 | |
Navarro et al | 225 | 50 | 45 | 14 | 49 | 14 |
5-FU (mg/m2 CI) | Oxaliplatin (mg/m2) | |||||
Ryan et al | 200 | MTD: 60 weekly | 50.4 | 38 | - | 25 |
Aschele et al | 200-225 | MTD: 60 weekly | 50.4 | 16 | 84 | 28 |
Turrito et al | 300 | 80 wk 1, 3, 5 | 45 | - | 65 | 15 |
Capecitabinec (mg/m2 bid) | Oxaliplatin (mg/m2) | |||||
Rodel et al | 825 d 1-14 and 22 - 35 | 50 d 1, 8, 22 | 50.4 | 6 | 55 | 19 |
Machiels et al | 825 bid continuous | 50 weekly | 45 | 30 | - | 14 |
- Citation: Diaz-Gonzalez JA, Arbea L, Aristu J. Rectal cancer treatment: Improving the picture. World J Gastroenterol 2007; 13(44): 5805-5812
- URL: https://www.wjgnet.com/1007-9327/full/v13/i44/5805.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i44.5805