Well to moderately differentiated HCC manifesting hyperattenuation on both CT during arteriography and arterial portography

Figure 4 Histological features of a US-guided biopsy of a hyperechoic nodule in S2. A: Well- to moderately-differentiated HCC characterized by more than two-fold the cellularity of the non-tumorous area, fatty change, clear cell change and mild cell atypia with a thin to mid-trabecular pattern (HE×100); B: Immunohistochemical finding, HSP70 partly positive HCC cells; C: Immunohistochemical finding, CAP2 strongly positive HCC cells; D: Immunohistochemical staining of CD34 in the sinusoidal blood space is positive, showing capillarization; E: Immunohistochemical staining of CD68 Kupffer cells in the sinusoidal blood space is relatively less positive; F: Non-HCC area of immunohistochemical staining of CD68 Kupffer cells in the sinusoidal blood space.