Genetic polymorphisms of ADH2 and ALDH2 association with esophageal cancer risk in southwest China

Table 1 Characteristics of patients and controls n (%)

Characteristic	Patients n = 191	Controls n = 198	P1	OR (95% CI)2
Age (yr)
< 50	28 (14.7)	84 (42.9)
50-64	118 (61.7)	67 (33.4)	P < 0.001	-
≥ 65	45 (23.6)	47 (23.7)
Mean age (SD)	58.3 (8.3)	52.8 (13.2)	-	-
Sex
Male	126 (66.0)	122 (61.6)	P = 0.372	-
Female	65 (34.0)	76 (38.4)		-
Smoking status
Non-smokers3	75 (39.3)	121 (61.1)	P < 0.001	1.00 (References)
Current smokers	116 (60.7)	77 (38.9)		3.76 (2.01-6.73)
Alcohol drinking status
Non-drinkers4	80 (41.9)	128 (64.7)		1.00 (References)
Current alcohol drinkers	111 (58.1)	70 (35.3)	P < 0.001	3.16 (1.91-5.24)

¹P value by chi-square test;

²ORs for smoking and drinking were adjusted for age and sex, rapid food eating, quality of drinking water, consumption of fresh fruits, vegetable and eggs;

³Non-smokers including ex-smokers;

⁴Non-drinkers including ex-drinkers.